Using Ontologies for Visualizing Design Heterogeneity in Human Studies

Ida Sim

University of California, San Francisco

The human studyome is the totality of all human studies worldwide, encompassing all interventional, observational and qualitative research on human subjects. The human studyome is one of the most valuable sources of knowledge for advancing the understanding of diseases and treatments. Dr. Sim will discuss her NCBO Driving Biological Project that sought to use ontologies to visualize design heterogeneity in randomized trials for comparative effectiveness researchers. She will also discuss some observations on the benefits and challenges of applying ontologies and ontology tools to computerizing the human studyome and to clinical research in general.

Bio: Dr. Ida Sim is Associate Professor of Medicine at UCSF and Director, UCSF Center for Clinical and Translational Informatics. She received her MD and her PhD in Medical Informatics from Stanford University. Dr. Sim's research focus is on knowledge-based technologies for evidence-based practice, especially in the ontological representation of human studies for advancing clinical and translational research. In policy work, Dr. Sim was the founding Project Coordinator of the World Health Organization's International Clinical Trials Registry Platform, which sets global standards on clinical trial registration and reporting. She is a recipient of United States Presidential Early Career Award for Scientists and Engineers (PECASE), and is a Fellow of the American College of Medical Informatics.